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Today, approximately 200 million people around the world are required to regularly check blood sugar levels every day, and this number is increasing day by day. If hyperglycaemia and hypoglycemia occur as a result of blood sugar level abnormalities, serious tissue and organ damage and, most importantly, vital risks can occur. In generally, blood glucose level measurement methods are divided into three categories, which are invasive, minimally invasive and non-invasive. In invasive methods people need to measure blood glucose levels by drilling their fingers, squeezing blood droplets on test strips and treating the results with portable glucometers. The process can be uncomfortable and complicated and has to be repeated many times each day. By using minimally invasive methods, the glucose ratio is determined by the help of tissue fluid or very little blood. Actually this method is uncomfortable for human life too. For this reason, there is a growing need for a new generation of non-invasive glucose-level monitoring systems in which the glucose level can be reliably determined. The goal of the ongoing works in literature are to prevent or delay early diagnosis and complications, rather than to treat the diabetes. This review giving a comprehensive knowledge about non-invasive design methods used in the literature.General definitions are given for each of the design methods. Scientists, laboratories and universities have been working on the design of non-invasive glucometer with various methods, yet there is no product that can measure with high accuracy.

International Conference on Advanced Technologies, Computer Engineering and Science
ICATCES

Ercan Mengüç Selcuk Helhel